British Air Force Typhoon FGR4s have operated alongside French warplanes in a coordinated attack on an subterranean weapons facility in Syrian territory employed by the IS group, according to the UK's MoD.
The facility, identified by intelligence, was assessed as containing munitions and bombs, the statement said, and was located in hills just above the ancient city of Palmyra in the heart of Syria.
"Our fighter planes used Paveway IV guided bombs to target a series of entry passages leading to the facility... early reports indicate the objective was successfully hit," the MoD said.
There was no evidence of any harm to civilians in the operation conducted Saturday night and all the aircraft returned to base without incident, the defence officials confirmed.
The Typhoon FGR4s were supported by a Voyager refuelling tanker.
Daesh - also known as the so-called Islamic State - imposed extremist governance over significant areas in Syria and Iraq until 2019.
"This operation demonstrates British leadership, and resolve to operate in unison with our partners, to stamp out any re-emergence of the terrorist group and their harmful and extremist ideologies in the Middle East," UK Defence Secretary John Healey remarked.
UK warplanes have performed surveillance missions over Syria to "deter any efforts to regroup" of IS after its routing at the Baghuz confrontation in 2019, the MoD reported.
"I want to thank all the members of British forces involved in this operation for their expertise and their courage," Healey added. "They were part of a great many British troops deployed over Christmas and New Year. This mission, to take out dangerous terrorists who threaten our safety, shows how UK forces are ready to step up, all year round, ensuring Britain's security domestically and influential overseas."
During December, the American forces executed what it described as a "massive strike" against IS targets in Syria, following an attack claimed the lives of two US servicemembers and a local interpreter in Palmyra.
The UN estimates IS still boasts between 5,000 and 7,000 combatants in Iraq and Syria.
